| Related Initiatives Overview
Several ongoing initiatives support and complement The Cancer Genome Atlas Project. Read more about these related programs below.
Description of Related Initiatives & Links for More Information
NCI Related Initiatives
cancer Biomedical Informatics Grid® (caBIG®)
caBIG® is a voluntary network or grid connecting individuals and institutions to enable the sharing of data and tools, creating a World Wide Web of cancer research. To learn more about caBIG®, visit https://cabig.nci.nih.gov/.
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Cancer Genetic Markers of Susceptibility (CGEMS)
The CGEMS project is an NCI enterprise initiative to conduct whole genome association studies to identify genes giving rise to risk for different cancer types. The project is designed to capitalize on new knowledge of human genetic variation and technical advances in ultra-high-throughput genotyping. To learn more about the CGEMS project, visit http://cgems.cancer.gov/.
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Cancer Genome Anatomy Project (CGAP)
The goal of CGAP is to provide researchers with a variety of resources to improve detection, diagnosis and treatment for the patient. By collaborating with scientists worldwide, CGAP seeks to increase its scientific expertise and expand its databases for the benefit of all cancer researchers. To learn more about CGAP, visit http://cgap.nci.nih.gov/.
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Clinical Proteomic Technologies for Cancer (CPTC)
The CPTC initiative is aimed at optimizing current proteomic technologies and developing the new technologies, reagents, systems and working consortia needed to significantly advance the field of cancer proteomics research. To learn more about the CPTC initiative, visit http://proteomics.cancer.gov.
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International Cancer Genome Consortium (ICGC)
The ICGC is working with scientists across the world to generate comprehensive catalogs of genomic abnormalities (somatic mutations, abnormal expression of genes, epigenetic modifications) in tumors from 50 different cancer types and/or subtypes. To learn more about the ICGC, visit http://icgc.org/home.
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Office of Biorepositories and Biospecimen Research (OBBR)
Established in 2005, the NCI OBBR is responsible for developing a common biorepository infrastructure that ensures the availability of high-quality, well-annotated biospecimens and promotes resource sharing and team science, in order to facilitate multi-institutional, high-throughput genomic and proteomic studies. To learn more about OBBR, visit http://biospecimens.cancer.gov.
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Repository of Molecular Brain Neoplasia Data (REMBRANDT)
REMBRANDT is a robust bioinformatics initiative that leverages data warehousing technology to host and integrate clinical and functional genomics data from clinical trials involving patients suffering from gliomas. REMBRANDT provides researchers the ability to perform ad hoc querying and reporting across multiple data domains, such as gene expression, chromosomal aberrations and clinical data. To learn more about REMBRANDT, visit http://caintegrator-info.nci.nih.gov/rembrandt.
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Therapeutically Applicable Research to Generate Effective Targets (TARGET)
The goal of NCI's TARGET Initiative is to identify valid therapeutic targets in childhood cancers so that new, more-effective treatments can be rapidly developed. To learn more about TARGET, visit http://target.cancer.gov/.
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NHGRI Related Initiatives
Encyclopedia Of DNA Elements (ENCODE) Project
The goal of the Encyclopedia of DNA Elements project is to identify all of the functional elements of the human genome. To learn more about ENCODE, visit http://www.genome.gov/10005107.
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Ethical, Legal and Social Implications (ELSI) Research Program
The Ethical, Legal and Social Implications Research Program was established in 1990 as an integral part of the Human Genome Project to foster basic and applied research on the ethical, legal and social implications of genetic and genomic research for individuals, families and communities. To learn more about the ELSI Research Program, visit http://www.genome.gov/10001618.
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Genetic Variation Program
The Genetic Variation program supports research on genetic variation and how it relates to diseases, responses to drugs and environmental factors. To learn more about the Genetic Variation Program, visit http://www.genome.gov/10001551.
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Genome Sequencing Program
The Genome Sequencing Program is responsible for the administration and support of research directed to the highly efficient construction of physical maps, large-scale sequencing and genomic resource production for entire genomes. To learn more about the Genome Sequencing Program, visit http://www.genome.gov/10001691.
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Genome Technology Program
The Genome Technology program supports research to develop new methods, technologies and instruments that enable rapid, low-cost determination of DNA sequence, SNP genotyping and functional genomics experiments. To learn more about the Genome Technology Program, visit http://www.genome.gov/10000368.
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International Cancer Genome Consortium (ICGC)
The ICGC is working with scientists across the world to generate comprehensive catalogs of genomic abnormalities (somatic mutations, abnormal expression of genes, epigenetic modifications) in tumors from 50 different cancer types and/or subtypes. To learn more about the ICGC, visit http://icgc.org/home.
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International HapMap Project
The sequence of the entire human genome has made possible our current effort to develop a haplotype map of the human genome. The haplotype map, or "HapMap," is a tool that is allowing researchers to find genes and genetic variations that affect health and disease. To learn more about the International HapMap Project, visit http://www.genome.gov/10001688.
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